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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 29.39
Human Site: S936 Identified Species: 40.42
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S936 T P T M S R S S S I S G V D M
Chimpanzee Pan troglodytes XP_526227 1093 122795 S936 T P T M S R S S S I S G V D M
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S935 T P T M S R S S S I S G V D M
Dog Lupus familis XP_533766 1089 122761 S932 S T P T M S R S S S I S G V D
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 S934 T P T M S R S S S I S G V D A
Rat Rattus norvegicus NP_446123 1093 121882 S936 T P T M S R S S S L S G V D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 S949 T P T L S R S S S I S G V D M
Chicken Gallus gallus O42184 1433 161009 R1207 Q L L E M K K R E S T L K K E
Frog Xenopus laevis Q5PQ23 649 75475 T502 E K L H Q Q T T E N T C L R L
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 S979 P S L S R S S S V S G A D H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 A785 G G M I D W Q A D D L D C A S
Honey Bee Apis mellifera XP_394037 1326 150590 V1051 S E E L S E S V S M A T K P L
Nematode Worm Caenorhab. elegans P02566 1966 225108 V1570 L E A E E S K V L R A Q V E V
Sea Urchin Strong. purpuratus XP_785821 1176 131318 S1020 P S P S S R A S T P V H S E I
Poplar Tree Populus trichocarpa XP_002303293 975 109171 F828 G S I E E S Y F L Q A S L D T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 S809 R K L S S A S S L G S M E E S
Baker's Yeast Sacchar. cerevisiae P47166 707 81153 L560 I P E E A A A L Q A I R E G E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 100 13.3 N.A. 93.3 93.3 N.A. 93.3 0 0 13.3 N.A. 0 20 6.6 20
P-Site Similarity: 100 100 100 20 N.A. 93.3 100 N.A. 100 13.3 40 13.3 N.A. 13.3 53.3 26.6 46.6
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 0 6 12 12 6 0 6 18 6 0 6 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 6 6 0 0 % C
% Asp: 0 0 0 0 6 0 0 0 6 6 0 6 6 42 6 % D
% Glu: 6 12 12 24 12 6 0 0 12 0 0 0 12 18 12 % E
% Phe: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % F
% Gly: 12 6 0 0 0 0 0 0 0 6 6 36 6 6 0 % G
% His: 0 0 0 6 0 0 0 0 0 0 0 6 0 6 0 % H
% Ile: 6 0 6 6 0 0 0 0 0 30 12 0 0 0 6 % I
% Lys: 0 12 0 0 0 6 12 0 0 0 0 0 12 6 0 % K
% Leu: 6 6 24 12 0 0 0 6 18 6 6 6 12 0 12 % L
% Met: 0 0 6 30 12 0 0 0 0 6 0 6 0 0 30 % M
% Asn: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % N
% Pro: 12 42 12 0 0 0 0 0 0 6 0 0 0 6 0 % P
% Gln: 6 0 0 0 6 6 6 0 6 6 0 6 0 0 0 % Q
% Arg: 6 0 0 0 6 42 6 6 0 6 0 6 0 6 0 % R
% Ser: 12 18 0 18 53 24 53 59 48 18 42 12 6 0 12 % S
% Thr: 36 6 36 6 0 0 6 6 6 0 12 6 0 0 6 % T
% Val: 0 0 0 0 0 0 0 12 6 0 6 0 42 6 6 % V
% Trp: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _